Đánh giá khả năng kháng oxy hóa, ức chế enzyme α-amylase và α-glucosidase của các cao chiết từ lá cây núc nác (Oroxylum indicum L.)

Đái Thị Xuân Trang * , Nguyễn Thị Thúy Oanh , Trần Chí Linh , Lê Thanh Phương Thảo , Trần Thanh Mến và Nguyễn Trọng Tuân

* Tác giả liên hệ (dtxtrang@ctu.edu.vn)

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Ngày nhận bài: 10-07-2019
Ngày nhận bài sửa: 14-09-2019
Ngày duyệt đăng: 25-12-2019
Ngày xuất bản: 25-12-2019
Title: Antioxidant activity and α-amylase, α-glucosidase inhibiting activities of the extracts from Oroxylum indicum (L.) leaves
DOI: 10.22144/ctu.jvn.2019.155
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Trích dẫn
Trang, Đ. T. X., Oanh, N. T. T., Linh, T. C., Thảo, L. T. P., Mến, T. T., & Tuân, N. T. (2019). Đánh giá khả năng kháng oxy hóa, ức chế enzyme α-amylase và α-glucosidase của các cao chiết từ lá cây núc nác (Oroxylum indicum L.). Tạp chí Khoa học Đại học cần Thơ, 55(6), 29-36. https://doi.org/10.22144/ctu.jvn.2019.155
Số báo
Tập. 55 Số. 6 (2019)
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Tự nhiên

Abstract

The chemical composition of the leaf extracts of Oroxylum indicum (L.) was found to contain alkaloids, flavonoids, glycosides, tannins and steroids. The total polyphenol and flavonoid contents of Oroxylum indicum (L.) leaves in ethyl acetate extracts (60.56±0.30 mg GAE/g and 235.29±2.88 mg QE/g, respectively) were higher than those in the other three extracts including ethanol, n-hexane and dichloromethane. The previous study was performed to demonstrate the antioxidant activity and enzyme inhibition of ethanol, n-hexane, dichloromethane and ethyl acetate extracts of Oroxylum indicum (L.). The results showed that ethyl acetate extract has antioxidant activity and inhibitory activity of α-amylase, α-glucosidase enzymes higher than other extracts.
Keywords: α-amylase, α-glucosidase, antioxidant, Oroxylum indicum (L.)

Tóm tắt

Thành phần hóa học của lá cây Núc Nác được xác định có chứa các nhóm chất alkaloid, flavonoid, glycoside, tannin, steroid và triterpenoid. Hàm lượng polyphenol (60,56±0,30 mg GAE/g cao chiết) và flavonoid (235,29±2,88 mg QE/g cao chiết) trong cao ethyl acetate nhiều hơn cao chiết từ ba dung môi còn lại là ethanol, n-hexane và dichloromethane. Kết quả đánh giá hoạt tính kháng oxy hóa và ức chế enzyme của các cao chiết ethanol, n-hexane, dichloromethane và ethyl acetate từ lá cây Núc Nác: cao ethyl acetate có hoạt tính kháng oxy hóa và ức chế hoạt động của các enzyme α-amylase và α-glucosidase mạnh nhất trong các cao chiết được khảo sát.
Từ khóa: α-amylase, α-glucosidase, kháng oxy hóa, Oroxylum indicum L.

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