Simulation of sensitivity of optical sensor based on prism using copper induced surface plasmon resonance for disease diagnosis

Nguyen Tan Tai *

* Corresponding author (nttai60@tvu.edu.vn)

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Received: 04 Aug 2017
Revised: 08 Nov 2017
Accepted: 29 Nov 2017
Published: 29 Nov 2017
Title: Simulation of sensitivity of optical sensor based on prism using copper induced surface plasmon resonance for disease diagnosis
DOI: 10.22144/ctu.jvn.2017.136
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How to Cite
Tài, N. T. (2017). Simulation of sensitivity of optical sensor based on prism using copper induced surface plasmon resonance for disease diagnosis. CTU Journal of Science, (53), 13-18. https://doi.org/10.22144/ctu.jvn.2017.136
Issue
No. 53 (2017)
Section
Engineering Technology

Abstract

The paper is to present the simulation results of the surface plasmon resonance (SPR) sensor using transfer matrix method for multilayer films. Surface plasmon resonance can be generated by depositing one layer of metal with thickness of less than 100 nm. The metal, which is Cu, is deposited on the bottom of the prism for sensing surface with the optimal thickness of around 50 nm. An optical sensor based on Cu deposited has the detection capability of about 99,5o/RIU, offering high sensitivity and easy fabrication of optical sensors. Moreover, the SPR sensor can be applied to measure biological elements such as fibrinogen protein, tau-protien concentrations in real-time manner for disease diagnosis. The SPR optical sensor has some advantages such as, small, low cost, easy manufacture and relatively high sensitivity.
Keywords: Diagnosis, Optical sensor, Surface plasmon resonance, Sensitivity

Tóm tắt

Bài báo trình bày kết quả mô phỏng cho cảm biến quang học được phủ đồng (Cu) để tạo hiệu ứng cộng hưởng bề mặt sử dụng ma trận truyền tải cho nhiều lớp kim loại. Hiệu ứng cộng hưởng bề mặt được tạo ra bằng cách phủ một lớp kim loại với độ dày thích hợp (d ≤ 100 nm) trên bề mặt một chất có chiết suất lớn như lăng kính. Kết quả mô phỏng cho thấy lớp phủ Cu với độ dày khoảng 50 nm đã cho thấy thành phần sóng từ trường nằm ngang (transverse magnetic field) tạo nên hiệu ứng cộng hưởng bề mặt với độ nhạy khoảng 99,5o/RIU. Kết quả này có thể dùng để tiến hành thực nghiệm chế tạo cảm biến quang học dùng để phát hiện và đo lường nồng độ các protein trong máu như fibrinogen (bệnh tim), tau-protein (bệnh mất trí nhớ) để ứng dụng trong chẩn đoán bệnh, giá thành rẻ hơn và độ nhạy tương đối cao.
Từ khóa: Cảm biến quang học, chẩn đoán, độ nhạy, hiệu ứng cộng hưởng bề mặt

Article Details

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